Search results for "Peperomia vulcania"

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Constituents of Peperomia vulcanica Baker & C. H. Wright (Piperaceae) with antiparasitic activity

2021

Abstract The investigation of the CH2Cl2-MeOH (1:1) extract of Peperomia vulcanica which showed antileishmanial activity during preliminary screening led to the isolation of two previously unknown compounds named peperolignan (1) and peperotannin (2) along with 13 known compounds. Their structures were determined on the basis of their spectroscopic data. The isolated compounds were assessed in vitro for their antileishmanial and antiplasmodial activities against Leishmania donovani 1S (MHOM/SD/62/1S) promastigotes and the Plasmodium falciparum chloroquine-sensitive 3D7 strain (Pf3D7), respectively. They were also assessed for their cytotoxicity on Raw 264.7 macrophage cells. The mixture of …

Antiparasiticmedicine.drug_classLeishmania donovaniPeperomia vulcaniaPlant Science01 natural sciencesBiochemistryAntiplasmodialmedicineAntileishmanialCytotoxicityIC50biologyTraditional medicine010405 organic chemistryChemistryPeperomia vulcanicaPlasmodium falciparumPeperotanninPiperaceaePiperaceaebiology.organism_classificationPeperolignanIn vitro0104 chemical sciences010404 medicinal & biomolecular chemistryAgronomy and Crop ScienceBiotechnologyPhytochemistry Letters

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